Membrane Pharmacy Structure Dynamics

Research group : Priv.Doz. Dr. Thomas Nawroth

Thesis list

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old list of Diploma-, PhD-, Habilitation- thesis ... former Membrane Protein Structure Dynamics group

Dep.: = Department (C = chemistry; B = biology)

Ref.	Author, First-Name	Year	Type	Dep.	Title (original, german)	Title (translated)	Actualized abstract	Online available
T1	Nawroth, Thomas	1984	PhD	C	Neutronenkleinwinkelstreuung der freien und membrangebundenen ATP-Synthase und ihres F1-Teils	Neutron small angle scattering of solubilized and membrane bound ATP-synthase and its F1-fragment
T2	Pabst, Rainer	1985	PhD	C	Präparation von delipidisiertem Bacteriorhodopsin und Rekonstitution in künstliche Modellmembranen	Preparation of monomeric Bacteriorhodopsin and reconstitution in artificial model membranes
T3	Wagner, Norbert	1985	PhD	C	Einbau und Charakterisierung von funktionell gekoppleten Membranproteinen in Modellmembranen aus natürlichen und polymerisierbaren Lipiden	Reconstitution and characterization of functional coupled membrane proteins in model membranes from natural and polymerizable lipids
T4	Neidhardt, Axel	1986	Dipl	C	Vergleichende Untersuchung nativer und d-Untereiheit-freier F1ATPase aus Micrococcus luteus mit Röntgenkleinwinkelstreuung und enzymkinetischen Methoden	Comparison of native and inhibitor protein (d) free F1ATPase from Micrococcus luteus by X-ray small angle scattering and enzyme kinetics
T5	Steinborn, Andrea	1986	Dipl	B	Untersuchungen zur Ermittlung von Membranschäden infolge Trocknungs und Vakuum-exposition	Membrane demages after dry and vacuum exposition
T6	Eul, Ursula	1986	PhD	C	Zur Struktur und Funktion freier und membrangebundener ATP-Synthasen aus Rhodospirillum rubrum und Micrococcus luteus	On structure and function of free and membrane bound ATP-synthases from Rhodospirillum rubrum and Micrococcus luteus
T7	Zwicker, Klaus	1987	Dipl	C	Photochemische Erzeugung und Bestimmung von Protonengradienten an vesikulären Lipidmembranen	Photochemical generation of a transmembrane proton gradient and its estimation with dye liposomes
T8	Zölch, Barbara	1988	Dipl	B	Phospholipide aus Mycel und Konidien von Aspergillen bei verschiedenen Wachstumstemperaturen	Phospholipids and fatty acid composition of mycelium and conidiae of Aspergillus during cold adaption
T9	Gutweiler, Mathias	1988	PhD	C	Struktur und Funktion der ATP-Synthase aus Rhodospirillum rubrum in energetisch gekoppelten Modellmembranen	Structure and function of ATP-synthase from Rhodospirillum rubrum in energetically coupled model membranes
T10	Hamar, Friederike	1989	Dipl	C	Protonenpermeation und elektrochemische Protonenpotentialdifferenz in rekonstituierten Proteoliposomen aus monomerem Bacteriorhodopsin und ATP-Synthase	Proton permeation and electrochemical proton potential difference in reconstituted proteoliposomes from monomeric Bacteriorhodopsin and ATP-synthase
T11	Klein, Marion	1989	Dipl	B	Wirkung amphiphiler Pharmaka auf den Protonentransport durch Lipidmembranen	Effect of amphiphilic drugs on the proton permeability of lipid membranes
T12	Schrattenholz, André	1990	PhD	B	Isolation, Charakterisierung und Rekonstitution des Cytochrom-o-Komplexes aus Chromatophoren des photosynthetischen Bakteriums Rhodospirillum rubrum FR1	Isolation, characterization and reconstitution of the Cytochrome-o complex from the photosynthetic bacterium Rhodospirillum rubrum FR1
T13	Burhop, Kai-Uwe	1990	Dipl	C	Oxidase-Aktivität und Redox-Eigenschaften des Cytochrom-o-Komplexes aus Rhodospirillum rubrum FR1	Oxidase activity and redox properties of the Cytochrome-o complex from Rhodospirillum rubrum FR1
T14	Neidhardt, Axel	1991	PhD	C	Strukturelle Dynamik im Reaktionszyklus der F1ATPase aus Micrococcus luteus	Structural dynamics in the reaction cycle of F1ATPase from Micrococcus luteus
T15	Zwicker, Klaus	1992	PhD	C	Isolation der ATP-Synthase aus Micrococcus luteus und funktionelle Rekonstitution in Modellmembranen	Isolation of ATP-synthase from Micrococcus luteus and functional reconstitution in model membranes
T16	Eßwein, Petra	1992	Dipl	B	Isolierung einer redoxaktiven Ubichinol-Oxidase aus vitalen Kulturen von Rhodospirillum rubrum FR1	Isolation of a redox-active Ubiquinol-oxidase from Rhodospirillum rubrum FR1
T17	Grüber, Gerhard	1992	Dipl	B	Funktionelle Variabilität der freien und rekonstituierten ATP-Synthase aus Micrococcus luteus	Functional variability of free and reconstituted ATP-synthase from Micrococcus luteus
T18	Heinz, Gerd	1992	Dipl	B	Präparation der Cytochrom-c Oxidase aus Micrococcus luteus	Preparation of Cytochrom-c Oxidase from Micrococcus luteus
T19	Grüber, Gerhard	1995	PhD	B	Dynamik und Regulation der ATP-Synthase aus Micrococcus luteus	Dynamics and regulation of ATP-synthase from Micrococcus luteus
T20	Nawroth, Thomas	1995	Habil	C	Strukturdynamik und Funktion Protonen-transportierender Membranproteine	Structure dynamics and function of proton translocating membrane proteins
T21	Heinz, Gerd	1995	PhD	B	Struktur und Funktion der Cytochrom-c Oxidase aus Micrococcus luteus	Structure and function of Cytochrome-c oxidase from Micrococcus luteus
T22	Eßwein, Petra	1996	PhD	B	Struktur und Funktion der Ubichinol-Oxidase aus Rhodospirillum rubrum	Structure and function of Ubiquinol-oxidase from Rhodospirillum rubrum
T23	Lauer, Iris	2000	PhD	C	Strukturdynamik der ATP-Synthase aus Micrococcus luteus im Nukleotid- Reaktionszyklus und dessen Regulation	Structure dynamics of ATP-synthases from Micrococcus luteus in the nucleotide reaction cycle and its regulation
T24	Meinert, Heike	***	PhD	C	Dynamik der Struktur, Oberflächenexposition und Funktion des Bacteriorhodopsins in Abhängigkeit von Umgebungsfaktoren	Dynamics of structure, surface and function of Bacteriorhodopsin during dry-, UV and space exposition

Statistics:

The thesis T1 - T23 cover 23 of the 29 thesis (80%), which were prepared in the membrane-protein & bioenergetics division of the Biochemistry Institute of the Gutenberg-University, Mainz between 1985 and 2000. This group is that part of the institute structure not covered by the groups of Prof. Dr. Dr. h.c. F. Fahrenholz (protein chemistry -biochemistry & receptors group), Prof. Dr. C. Koch-Brandt & PD. Dr. G. Klock (molecular biology & cell biology group ) , PD. Dr. O. Ullrich (molecular cell biology group), Prof. Dr. K. Dose (em.) (exobiology group), and Prof. Dr. P. Flesch (wine chemistry group). The rest (6 of 29 thesis = 20%) was prepared in Prof. Dr. H.-J. Schäfer's bioenergetics-photoaffinity labeling group. These are the thesis TS1 - TS6:

Ref.	Author, First-Name	Year	Type	Dep.	Title (original, german)	Title (translated)	Actualized abstract	Online available
TS1	Schaefer, Hans-Joachim	1991	Habil	C	Photoaktivierbare ATP-Analoge - Synthese und Anwendung zur Photoaffinitätsmarkierung und Photoaffinitätsvernetzung von ATP-Synthase-Komplexen	Photoactivalable ATP analogs - Synthesis and application for photoaffinity labeling and photoaffinity crosslinking of ATP-synthase complexes
TS2	Schuhen, Achim	1992	Dipl	B	Charakterisierung verschiedener F₁ATPasen mit Hilfe des trifunktionellen Nukleotidanalogons 3'-O-{3-[N-(4-Amido-2- nitrophenyl)- amino]- propionyl}- 2,8,-diazido-ATP	Charactization of several F₁ATPases with the trifunctional nucleotide analog 3'-O-{3-[N-(4-Amido-2- nitrophenyl)- amino]- propionyl}- 2,8,-diazido-ATP
TS3	Knoche, Maren	1994	Dipl	C	Photoaffinitätsmarkierung der ATP-synthase aus dem thermophilen Bakterium PS3 mit 2-Azido-1,N⁶-etheno-ATP	Photoaffinity labeling of the ATP-synthase of the thermophilic bacterium PS3 by 2-Azido-1,N⁶-etheno-ATP
TS4	Schuhen, Achim	1995	PhD	B	Photoaffinitätsmarkierung und Photoaffinitätsvernetzung der F₁-ATPase aus dem thermophilen Bacillusstamm PS3 durch fluoreszierende, photoaktivierbare Dinukleotide	Photoaffinity labeling and photoaffinity crosslinking of the F₁-ATPase of the thermophilic bacillus strain PS3 by fluorescent, photoactivalable dinucleotides
TS5	Eger, Olaf	1997	Dipl	C	Photoaffinitätsmarkierung einer bakteriellen F₁-ATPase mit biotinylierten, photoaktivierbaren ATP-Analoga	Photoaffinity labeling of a bacterial F₁-ATPase with biotinylated, photoactivalable ATP analogs
TS6	Knoche, Maren	1998	PhD	C	Photoaffinitätsvernetzung der Phosphofruktokinase aus Saccharomyces cerevisiae durch photoaktivierbare Nukleotidanaloga	Photoaffinity crosslinking of the Phosphofructokinase of Saccharomyces cerevisiae by photoactivalable nucleotide analogs

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email to: nawroth@MPSD.de update : 15.10.2010