Membrane Protein Structure Dynamics 

Research group : Priv.Doz. Dr. Thomas Nawroth 

   Papers and books

The actualized short abstracts may differ in the text from the original abstracts because of rewriting in order to avoid any copyright problems. Some objects are available online as *.PDF files. For reading you need the Adobe Acrobat 4.0 Reader (Trade Mark of Adobe Systems Inc.).

List: 

Ref. Authors year Title Reference short abstract ISBN (book) Online 
available
F1 Nawroth, T.; Dose, K. 1982 Application of a three-dimensional drawing procedure to the evaluation of series of protein samples after analysis by gel electrophoresis and other methods J. Chromatogr. 214, 126-130
F2 Hartmann, J.; Nawroth, T.; Dose, K. 1983 Formation of specific amino acid sequences during carbodiimide-mediated condensation of amino acids in aqueous solution, and computer-simulated sequence generation Origins of Life 14, 213-220
F3 Nawroth, T.; Conrad, H.; Vienken, J.; Dose, K. 1983 Neutron small angle scattering of matched proteoliposomes with incorporated FoF1ATPase complex from Rhodospirillum rubrum FR1. - An approach to the structure of membrane proteins in their natural environment Hoppe Seyler's Z. Physiol. Chem. 364, 923-931
F4 Dose, K.; Eul, U.; Nawroth, T.; Pabst, R.; Risi, S.; Wagner, N.; Conrad, H. 1984 Neutronenkleinwinkelstreuung der freien und membrangebundenen ATPase Berichte der Kernforschungsanlage Jülich, Jül-Spez-250, 660-673
F5 Pabst, R.; Nawroth, T.; Dose, K. 1984 Time-dependent monomerization of 
bacteriorhodopsin in Triton-X100 solutions analyzed by high-performance liquid chromatography
J. Chromatogr. 285, 333-341
F6 Conrad, H.; Dose, K.; Nawroth, T. 1989 Neutron small angle scattering of micelles from detergents suitable for the solubilization of native membrane proteins Physica 156 B, 474-476
F7 Nawroth, T.; Conrad, H.; Dose, K. 1989 Neutron small angle scattering of liposomes in the presence of detergents Physica 156 B, 477-480
F8 Nawroth, T.; Neidhardt, A.; Dose, K.; Conrad, H.; Munk, B.; Stuhrmann, H.B. 1989 Structural changes of F1ATPase detected by neutron and   X-ray small angle scattering Physica 156 B, 485- 488
F9 Nawroth, T.; Dose, K.; Conrad, H. 1989  Neutron small angle scattering of detergent solubilized and membrane bound ATP-synthase Physica 156 B, 489-492
F10 Nawroth, T. 1989 Interpretation of small angle scattering data by molecular models according to the 'finite volumes method' (FVM) Physica 156 B, 493-495
F11 Nawroth, T.; Dose, K.;Conrad, H.; Koch, H.; Ringsdorf, H. 1989 Neutron small angle scattering of monomeric and polymeric liposomes from synthetic lipids Physica 156 B, 496-498
F12 Schrattenholz, A.St.; Nawroth, T.; Dose, K. 1989 Isolation and partial characterization of a cytochrome-o complex from chromatophores of the photosynthetic bacterium Rhodospirillum rubrum FR1 Eur. J. Biochem. 181, 689-694
F13 Dose, K.; Nawroth, T.; Eul, U.; Hammar; F.; Neidhardt, A.; Risi, S.; Schrattenholz, A.St.; Zwicker, K. 1990 Statische und dynamische Konformationsänderungen von Proteinen: Untersuchung der ATP-Synthase und ihres F1-Teiles durch Neutronen- und Röntgenkleinwinkelstreuung in: "Erforschung kondensierter Materie und Atomphysik - Ergebnisberichte 1986-89 des BMFT", Deutsches Elektronensynchrotron DESY, Hamburg, Schriftenreihe "Naturwissenschaftliche Grundlagenforschung im Verbund mit Großgeräten", Ausgabe1, Ergänzungsband A, pp. 1781-1793 
F14 Neidhardt, A.; Nawroth, T.; Hütsch, M.; Dose, K. 1991 Structural dynamics of F1ATPase from Micrococcus luteus during the first reaction cycle of ATP-hydrolysis as estimated by time- resolved X-ray scattering FEBS Lett. 280, 179-182
F15 Nawroth, T. 1992 Membrane labeling by colored lipid-analogues and 
photoaffinity labeling of membrane proteins by colored hydrophobic azido-probes
Fresenius Z.Anal.Chem. 343, 173
F16 Nawroth, T.; Zwicker, K.; Dose, K. 1992 Bioluminescence analysis and numerical evaluation of ATP-synthesis by native and reconstituted membranes containing bacterial ATP-synthase Fresenius Z.Anal.Chem. 343, 174
F17 Deisinger, B.; Nawroth, T.; Zwicker, K.; Matuschka, S.; John, G.; Zimmer, G.; Freisleben, H.-J. 1993 Purification of ATP-synthase from beef heart mitochondria (F0F1) and co-reconstitution with monomeric bacteriorhodopsin into liposomes capable of light-driven ATP synthesis Eur. J. Biochem. 218, 377-383
F18 Grüber, G., Godovac-Zimmermann. J., Nawroth, T. 1994 ATP synthesis and hydrolysis of the ATP-synthase from Micrococcus luteus regulated by an inhibitor subunit and membrane energization Biochim.Biophys.Acta. 1186, 43-51
F19 Heinz, G.; Dose, K.; Nawroth, T. 1994 Purification of a Cytochrome aa3 terminal oxidase from protoplast vesicles (PMV) of Micrococcus luteus FEMS Microbiol.Lett. 124, 173-178
F20 Grüber, G.; Engelbrecht, S.; Junge, W.; Dose, K.; Nawroth, T. 1994 Purification and characterization of the inhibitory subunit (d) of the ATP-synthase from Micrococcus luteus FEBS Lett. 356, 226-228
F21 Dose, K.; Bieger-Dose, A.; Dillmann, R.; Gill, M.; Kerz, O.; Klein, A.; Meinert, H.; Nawroth, T.; Risi, S.; 
Stridde, C.
1995 ERA-Experiment 'Space Biochemistry'  Adv. Space Res. 8, 119-129
F22 Matuschka, S.; Zwicker, K.; Nawroth, T.; Zimmer, G. 1995 ATP-synthase from beef heart mitochondria: Isolation and functional reconstitution Arch. Biochem. Biophys. 322, 135-142
F23 Freisleben, H.-J.; Zwicker, K.; Jezek, P.; John, G.; Bettin-Bogutzki, A.; Ring, K.; Nawroth, T. 1995 Reconstitution of  bacteriorhodopsin and ATP-synthase from Micrococcus luteus  into liposomes of the purified main tetraetherlipid of Thermoplasma acidophilum: proton conductance and light-driven ATP synthesis Chem. Phys. Lipids 78, 137-147
Roessle, M.; Manakova, E.; Lauer, I.; Nawroth, T.; Gebhardt, R.; Narayanan, T.; Heumann, H. 1999 Time resolved SAXS study of conformational changes in the chaperonin system GroE ESRF Newsletter 33 (10), 10-11
Lauer, I.; Roessle, M.; Gebhardt, R.; Panine, P.; Boesecke, P.; Narayanan, T., Nawroth, T. 2000 Structure dynamics of working F1ATPase observed by time-resolved small angle X-ray scattering (TR-SAXS) ESRF Newsletter, submitted

 The short publications and expriment reports at DESY, ELETTRA, ESRF, ILL are refered in the short papers and science report lists.

Manuscripts in advance:

Dreschers, St.; Hotz-Wagenblatt, A.; Höhfeld, I.; Engels, I.; Friedberg, T.; Nawroth, T.; Gateff, E.
"Expression and functional analysis of the Drosophila blood tumor suppressor gene lethal(3)malignant blod neoplasm-1 [l(3)mbm-1]"

Nawroth, T. "Molecular modelling, simulation of structural dynamics and quantitative surface
analysis of proteins with the improved finite volumes method (FVM) - data analyis of X-ray or neutron small
angle scattering and photolabeling"

Nawroth, T.; Lauer, I.; Rössle, M.; Heumann, H.; Meier, G.; Goerigk, G.  "The cooperativity inhibitor azide expands the structure of ATP-synthase and F1ATPase form Micrococcus luteus - structural inhibitor titration with X-ray and neutron small angle scattering"


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email to: nawroth@MPSD.de   update : 15.10.2002